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Congenital smooth muscle hamartoma
Mon, 02/08/2010 - 08:08 — Mitsuhiro Sugiura M.D., Ph.D.
A one-year-old Japanese boy presented with brown macules on the waist.
| clinical image |  |  |  |
Diagnosis:
Congenital smooth muscle hamartoma
This lesion showed a positive pseudo-Darier sign (which is a transient piloerection and elevation of a lesion induced by rubbing and is observed especially in congenital smooth muscle hamartomas)
Immunohistochemical staining for α-SMA was positive in the tumor cells.