Janis M. Taube, M.D., Ph. D.

    Dr. Taube is the Director for the Dermatopathology Division and Fellowship at Johns Hopkins University. 

    She has a specific diagnostic interest in melanocytic lesions and gynecologic dermatopathology.  Dr. Taube’s research interests center on the immune evasion by melanoma, specifically studying the PD-L1/PD-1 axis, and the identification of potential biomarkers of response to novel immunotherapies. 

    She developed a robust IHC assay and methods of interpretation for studying PD-L1 as it relates to therapeutic response, and a version of this assay may soon be FDA approved.  Her ongoing laboratory efforts focus on further characterizing the local, pre-treatment tumor microenvironment using multiplex immunohistochemistry with the aim of developing rational treatment combinations and improving on patient selection algorithms.