Sean Klepper M.D.
Stephen Lyle, M.D., ...
- Often begins in infancy or early childhood, with a female predominance
- Associated with asthma and allergic disorders
- Presents with pruritus, erythema, scaling, excoriation, lichenification and superimposed lichen simplex chronicus
- In young children, most often affects the face and extensor surfaces of the extremities
- In older children and adults, flexural surfaces and neck are most commonly involved.
- Mild to moderate subacute to chronic spongiotic dermatitis
- Eosinophils and Langerhans cell clusters are absent, in contrast to allergic contact dermatitis.
- Follicular involvement is common.
- Due to the intense pruritus, the lesions are often rubbed or scratched, and secondary lichen simplex chronicus develops.