Atrophie blanche

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Also known as: livedoid vasculitis, segmental hyalinizing vasculitis, livedo reticularis with seasonal ulceration

    Clinical Features:

    • Most prevalent during the summer and winter
    • Usually affects middle-aged to elderly women
    • Most common on the lower legs
    • Presents with purpuric macules and papules which progress to painful ulcers
    • When the ulcers heal, they leave white atrophic areas.
    • There is often an associated livedo reticularis.

    Histologic Features:

    • Early lesions:
      • Fibrinoid material in the walls or lumina of blood vessels
      • Sometimes infarction with hemorrhage and inflammation
    • Late lesions:
      • Epidermal thinning
      • Dermal sclerosis
      • Thickening of vessel walls with intimal hyalinization
      • Occlusion of vessel lumina by intimal proliferation or fibrinoid material, sometimes with recanalization
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    Cases associated with this book:

  • Atrophie blanche
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection