Sean Klepper M.D.
Stephen Lyle, M.D., ...
Also known as: livedoid vasculitis, segmental hyalinizing vasculitis, livedo reticularis with seasonal ulceration
- Most prevalent during the summer and winter
- Usually affects middle-aged to elderly women
- Most common on the lower legs
- Presents with purpuric macules and papules which progress to painful ulcers
- When the ulcers heal, they leave white atrophic areas.
- There is often an associated livedo reticularis.
- Early lesions:
- Fibrinoid material in the walls or lumina of blood vessels
- Sometimes infarction with hemorrhage and inflammation
- Late lesions:
- Epidermal thinning
- Dermal sclerosis
- Thickening of vessel walls with intimal hyalinization
- Occlusion of vessel lumina by intimal proliferation or fibrinoid material, sometimes with recanalization