Atrophie blanche

Also known as: livedoid vasculitis, segmental hyalinizing vasculitis, livedo reticularis with seasonal ulceration

Clinical Features:

  • Most prevalent during the summer and winter
  • Usually affects middle-aged to elderly women
  • Most common on the lower legs
  • Presents with purpuric macules and papules which progress to painful ulcers
  • When the ulcers heal, they leave white atrophic areas.
  • There is often an associated livedo reticularis.

Histologic Features:

  • Early lesions:
    • Fibrinoid material in the walls or lumina of blood vessels
    • Sometimes infarction with hemorrhage and inflammation
  • Late lesions:
    • Epidermal thinning
    • Dermal sclerosis
    • Thickening of vessel walls with intimal hyalinization
    • Occlusion of vessel lumina by intimal proliferation or fibrinoid material, sometimes with recanalization

Cases associated with this book:

  • Atrophie blanche
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection