Cat scratch disease

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Caused by a gram-negative bacillus Bartonella henelae
    • Infection caused by a cat scratch or bite, most commonly on the hand or arm of children.
    • The initial skin lesion heals within two weeks, and patients may develop systemic symptoms.
    • Tender regional lymphadenopathy develops several weeks later, and the lymph nodes are more commonly biopsied than skin lesions.

    Histologic Features:

    • Skin lesions may show palisading granulomas surrounding areas of necrobiosis, sometimes with ulceration or epidermal hyperplasia.
    • Sometimes the findings are less characteristic, showing only perivascular or lichenoid lymphoplasmacytic or neutrophilic infiltrates.
    • Clumps of the bacilli may be visible on Warthin-Starry stain.
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    Cases associated with this book:

  • Cat scratch disease
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection