Sean Klepper M.D.
Artur Zembowicz M.D....
- Most commonly seen in elderly patients with significant atherosclerosis
- Frequently follows a medical procedure such as arterial catheterization, or may result from spontaneous detachment of atheromatous plaques.
- The lower extremities are most often affected.
- The clinical findings are variable, and can include livedo reticularis, frank gangrene or indurated nodules.
- Intravascular cholesterol clefts: needle-shaped spaces representing dissolved cholesterol crystals
- Foreign body giant cell reaction and intimal fibrosis may be seen.
- Sometimes only fibrin thrombi are present.