Also known as: venereal warts

Clinical Features:

• The most common sexually transmitted disease in the United States
• Most commonly caused by HPV types 6, 8, 16 and 18
• Common sites are the external genitalia, perianal and anal areas and cervix.
• The clinical appearance varies; cutaneous lesions are commonly soft sessile tumors which may be smooth or have a cauliflower-like surface.

Histologic Features:

• Polypoid lesion
• Prominent acanthosis
• Mild papillosis
• Broad, branching rete ridges, sometimes with pseudoepitheliomatous hyperplasia
• The upper epidermis may show koilocytosis with raisinoid nuclei.
• Focal parakeratosis in epidermal invaginations
• Dyskeratotic keratinocytes may be present.
• The dermis shows edema, vascular dilatation and a variable lymphocytic infiltrate.

Cases associated with this book:

condyloma
Author: Antonios Kafanas M.D.

Condyloma acuminatum
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection