Condyloma accuminatum

    Also known as: venereal warts

    Clinical Features:

    • The most common sexually transmitted disease in the United States
    • Most commonly caused by HPV types 6, 8, 16 and 18
    • Common sites are the external genitalia, perianal and anal areas and cervix.
    • The clinical appearance varies; cutaneous lesions are commonly soft sessile tumors which may be smooth or have a cauliflower-like surface.

    Histologic Features:

    • Polypoid lesion
    • Prominent acanthosis
    • Mild papillosis
    • Broad, branching rete ridges, sometimes with pseudoepitheliomatous hyperplasia
    • The upper epidermis may show koilocytosis with raisinoid nuclei.
    • Focal parakeratosis in epidermal invaginations
    • Dyskeratotic keratinocytes may be present.
    • The dermis shows edema, vascular dilatation and a variable lymphocytic infiltrate.
    External Links:

    Cases associated with this book:

  • condyloma
    Author: Antonios Kafanas M.D.

  • Condyloma acuminatum
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection