Cutaneous ossification

    Clinical Features:

    • Multiple etiologies:
      • Secondary to tissue injury, such as surgery, trauma or infection
      • Secondary to conditions which cause calcification: certain tumors (e.g., pilomatrixoma, BCC, chondroid syringoma), collagen vascular diseases (especially CREST syndrome), childhood dermatomyositis, old scars and scleroderma
      • Primary (osteoma cutis)
      • Miliary osteomas of the face: multiple small, hard papules related to acne scars
      • Nevus of Nanta: melanocytic nevus with osteoma
      • Various inherited disorders: Gardner's syndrome, Albright's hereditar osteodystrophy, alkaptonuria, ochronosis

    Histologic Features:

    • Dermal or subcutaneous trabeculae of lamellar bone
    • Osteoblasts and/or osteoclasts may be present.
    • Hematopoiesis is usually abesent from the marrow spaces, but may occasionally be seen.

    Cases associated with this book:

  • Cutaneous ossification
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection