Clinical Features:

• Intensely pruritic vesicular disease, presenting as a symmetrically distributed eruption on the extensor surfaces of extremities of young adults
• Associated with gluten-sensitive enteropathy

Histologic Features:

• Small subepidermal blisters
• Neutrophilic microabscess within the dermal papillae
• Superficial perivascular lymphocytic infiltrate
• Immunofluorescence shows granular deposits of IgA and C3 along the dermal-epidermal junction, localizing to the tips of the dermal papillae.

Cases associated with this book:

Dermatitis herpetiformis
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection

Reactive IgA antibodies by direct immunofluorescence in a skin biopsy after being in saline in room temperature for 14 days
Author: Dr. Sate Hamza MD, FRCPC

Conference: The Dermpath-l Mailing List Conference