Dermatomyositis

    Clinical Features:

    • Autoimmune disease characterized by erythematous macules and plaques occurring on light-exposed skin, as well as inflammation of skeletal muscle
    • It is associated with visceral malignancies in some cases.

    Histologic Features:

    • Epidermal atrophy and interface change
    • Mild lymphocytic inflammation and increased mucin deposition in the upper dermis
    • Perivascular and periadnexal inflammation may be seen.
    • The findings may be difficult to distinguish from those of lupus erythematosus.
    • Vascular deposition of complement on immunofluorescence is highly sensitive and specific for dermatomyositis.
    External Links:

    Cases associated with this book:

  • Dermatomyositis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection