Clinical Features:

• Autoimmune disease characterized by erythematous macules and plaques occurring on light-exposed skin, as well as inflammation of skeletal muscle
• It is associated with visceral malignancies in some cases.

Histologic Features:

• Epidermal atrophy and interface change
• Mild lymphocytic inflammation and increased mucin deposition in the upper dermis
• Perivascular and periadnexal inflammation may be seen.
• The findings may be difficult to distinguish from those of lupus erythematosus.
• Vascular deposition of complement on immunofluorescence is highly sensitive and specific for dermatomyositis.

Cases associated with this book:

Dermatomyositis
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection