Article Contributors:
Sean Klepper M.D.
Artur Zembowicz M.D....
Clinical Features:
- Cysts produced by dilation eccrine (eccrine hidrocystoma) or apocrine (apocrine hidrocystoma) with secondary epithelial proliferation
- Present as bluish papules or nodules
- Most common in the periorbital region
- More common in warm climates
Histologic Features:
- Eccrine hidrocystomas are lined by one to two layers of cuboidal to flattened epithelial cells, sometimes with squamous metaplasia, with or without connection to an eccrine duct.
- Apocrine hidrocystomas are lined by an inner layer of eosinophilic, columnar apocrine-type cells with decapitation secretion and an outer layer of myoepithelial cells. Papillary projections may sometimes be seen.
- In many instances a lesion cannot be readily defined as eccrine or apocrine, and this distinction is not essential from a clinical standpoint.
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