Eccrine hidrocystoma

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Clinical Features:

    • Cysts produced by dilation eccrine (eccrine hidrocystoma) or apocrine (apocrine hidrocystoma) with secondary epithelial proliferation
    • Present as bluish papules or nodules
    • Most common in the periorbital region
    • More common in warm climates

    Histologic Features:

    • Eccrine hidrocystomas are lined by one to two layers of cuboidal to flattened epithelial cells, sometimes with squamous metaplasia, with or without connection to an eccrine duct.
    • Apocrine hidrocystomas are lined by an inner layer of eosinophilic, columnar apocrine-type cells with decapitation secretion and an outer layer of myoepithelial cells.  Papillary projections may sometimes be seen.
    • In many instances a lesion cannot be readily defined as eccrine or apocrine, and this distinction is not essential from a clinical standpoint.

    External Links:

    Cases associated with this book:

  • Hidrocystoma
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Teaching Collection