Sean Klepper M.D.
Stephen Lyle, M.D., ...
Also known as: ashy dermatosis
- Considered by some to be a macular variant of lichen planus, based on the fact that the diseases sometimes coexist, and both have the same immunofluorescence findings
- Lesions are often widespread, although there is a predilection for the trunk.
- Presents as slowly progressive ash-colored to brown macular areas of hyperpigmentation
- Reported associations with paraphenylenediamine and HIV
- Lichen planus pigmentosus is considered by some to represent the same disease.
- Lichenoid lymphocytic infiltrate, much more sparse than in lichen planus, and may extend deeper into the dermis than in lichen planus
- Prominent melanin incontinence, which may be the only change in older lesions
- Basal vacuolar change
- Occasional Civatte bodies
- Immunofluorescence, as in lichen planus, shows IgM, IgG and complement deposition on dermal colloid bodies.