Also known as: nodular vasculitis, Bazin's disease
Clinical Features:
- Tender blue nodules, most often on the calves of obese women, sometimes related to cold exposure
- Controversial association with Mycobacterium tuberculosis
Histologic Features:
- Granulomatous lobular panniculitis with admixed lymphocytes, histiocytes and plasma cells
- There is often caseation necrosis, which may extend into the dermis and even epidermis, causing ulceration.
- Vasculitis is frequently, but not always, seen.