Clinical Features:

• Benign tumor presenting in the first two years of life
• Male predominance
• Solitary dermal and subcutaneous mass, most commonly on the shoulder, proximal upper limb, groin, back or forearm
• Presents as a firm, mobile sesion up to 10 cm in diameter
• May rarely recur if incompletely excised

Histologic Features:

• Ill-defined lesion mainly within the deep dermis and subcutis, composed of varying amounts of:
  • Disordered fibrous tissue: coarse collagen bundles with blood vessels and inflammation
  • Fascicles of myofibroblasts
  • Mature adipose tissue
  • Foci of myxoid tissue containing primitive mesenchymal cells with a whorled configuration

Cases associated with this book:

Fibrous hamartoma of infancy
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection