Clinical Features:

• Commonly presents on the face of middle-aged individuals, with a predilection for the nose
• Small skin-colored papule

Histologic Features:

• Slightly raised
• Well-circumscribed upper dermal lesion composed of collagenous stroma with increased vascularity and scattered spindled and/or mutinucleated cells
• Variants with granular or clear cell change exist.
• The epidermis is normal to slightly atrophic.
• The lesional cells stain for factor XIIIA and sometimes CD34.  They are negative for S-100.

Cases associated with this book:

Fibrous papule
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection