Follicular degeneration syndrome

    Clinical Features:

    • One of the clinicopathological entities group under the heading of "central centrifugal scarring alopecia."
    • Scarring alopecia begins on the crown or vertex and progressively spreads out.
    • Most common in black women

    Histologic Features:

    • Perifollicular lymphocytic inflammation and fibroplasia may be the only changes seen in early lesions.
    • Decreased follicle density
    • Concentric lamellar fibroplasia around follicles
    • Premature desquamation of the inner root sheath
    • Late lesions show destruction of follicles with residual fibrous tracts at the sites of the destroyed follicles.
    External Links:

    Cases associated with this book:

  • Follicular degeneration syndrome
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection