Granuloma annulare

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Peak incidence in children and young adults; female predominance
    • Annular papules, primarily on the dorsal surfaces of the extremities

    Histologic Features:

    • Fully developed lesions show dermal palisading granulomas surrounding degenerated collagen ("necrobiosis") and mucin.
    • Early lesions ("interstitial granuloma annulare") lack well-developed granulomas and instead show groups of macrophages dissecting between dermal collagen fibers.
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    Cases associated with this book:

  • Granuloma annulare
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection