Granulomas in immunodefficiency disorder

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Chronic granulomatous disease:

    Clinical Features:

    • Group of immune deficiency diseases caused by defects in the neutrophilic oxidative burst
    • Most commonly X-linked recessive

    Histologic Features:

    • When cutaneous granulomas are present in chronic granulomatous disease, they may or may not show caseation.
    • Granulomas may not be linked to an identifiable trigger, or may secondary to an infectious agent or foreign bodies.

    Cases associated with this book:

  • Chronic granulomatous disease
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Teaching Collection