Clinical Features:

• Benign tumor occurring almost exclusively in the genital area of women.  Rare examples have been reported in other locations and in men.

Histologic Features:

• Well-circumscribed dermal nodule
• Composed of complex branching papillae and tubules
• The epithelial lining of the papillae and tubules consists of two cell layers: an outer myoepithelial layer and an inner columnar layer which shows decapitation secretion.
• Nuclear pleomorphism and mitotic activity may sometimes be present, but the circumscribed nature of the lesion should lead to its recognition as a benign neoplasm.

Cases associated with this book:

Hidradenoma papilliferum
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection