Also known as: papular amyloidosis

Clinical Features:

• Hyperkeratotic papules on shins and other extensor surfaces on areas that are chronically rubbed
• Most common in young adults, with a predilection for persons of Chinese ancestry

Histologic Features:

• Globules of amyloid in the papillary dermis, usually more marked than in macular amyloidosis
• Papillary epidermal hyperplasia, often with hyperkeratosis and hypergranulosis
• Vascular proliferation is associated with the amyloid, with an upper dermal perivasular mononuclear infiltrate.
• There is often basal cell hydropic degeneration.
• Colloid bodies are often present.
• Melanin incontinence may be present.

Cases associated with this book:

Lichen amyloidosus
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection