Lichen amyloidosis

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Also known as: papular amyloidosis

    Clinical Features:

    • Hyperkeratotic papules on shins and other extensor surfaces on areas that are chronically rubbed
    • Most common in young adults, with a predilection for persons of Chinese ancestry

    Histologic Features:

    • Globules of amyloid in the papillary dermis, usually more marked than in macular amyloidosis
    • Papillary epidermal hyperplasia, often with hyperkeratosis and hypergranulosis
    • Vascular proliferation is associated with the amyloid, with an upper dermal perivasular mononuclear infiltrate.
    • There is often basal cell hydropic degeneration.
    • Colloid bodies are often present.
    • Melanin incontinence may be present.
    External Links:

    Cases associated with this book:

  • Lichen amyloidosus
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection