Lichen simplex chronicus

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Clinical Features:


    • A scaly plaque resulting from chronic trauma from rubbing or scratching the skin
    • Prurigo nodularis is the term used for the same process when referring to a localized nodule rather than a plaque.

    Histologic Features:


    • Prominent irregular acanthosis (the rete ridges are of varying length)
    • Hyperkeratosis, sometimes with focal parakeratosis, and hypergranulosis
    • Vertically oriented collagen fibers in the dermal papillae, often with increased fibroblasts
    • Superficial perivascular lymphocytic infiltrate
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    Cases associated with this book:

  • Lichen simplex chronicus
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Teaching Collection