Also known as: Blaschko linear acquired inflammatory skin eruption (BLAISE)

Clinical Features:

• A self-limited dermatosis usually presenting in spring or summer
• Most common in children, with a female predominance
• Presents as a unilateral eruption of Nscaly papules on the limbs which coalesce into a linear or curved band
• Nail changes may occur, including onycholysis, splitting or nail loss.
• Often resolves leaving hypo- or hyperpigmentation
• Associated with atopy in up to 50% of cases

Histologic Features:

• Early lesions may show only nonspecific mild chronic dermatitis.
• Other lesions may closely resemble lichen planus or lichen planopilaris.
• In more prototypical, established lesions, however, there is a spongiotic dermatitis with lichenoid and interface features:
  • Parakeratosis
  • Normal to slightly acanthotic epidermis
  • Spongiosis
  • Basal vacuolar change
  • Lymphocytic exocytosis
  • Satellite cell necrosis
  • Marked upper dermal as well as superficial and deep perivascular lymphohistiocytic infiltrate

Cases associated with this book:

12 year old boy with linear papules on extremities
Author: Svetlana Faktorovich

clinical image

Conference: Tufts First Year Medical Student's Dermatopathology Elective

Lichen striatus
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection