Sean Klepper M.D.
Artur Zembowicz M.D....
Also known as: Blaschko linear acquired inflammatory skin eruption (BLAISE)
- A self-limited dermatosis usually presenting in spring or summer
- Most common in children, with a female predominance
- Presents as a unilateral eruption of Nscaly papules on the limbs which coalesce into a linear or curved band
- Nail changes may occur, including onycholysis, splitting or nail loss.
- Often resolves leaving hypo- or hyperpigmentation
- Associated with atopy in up to 50% of cases
- Early lesions may show only nonspecific mild chronic dermatitis.
- Other lesions may closely resemble lichen planus or lichen planopilaris.
- In more prototypical, established lesions, however, there is a spongiotic dermatitis with lichenoid and interface features:
- Normal to slightly acanthotic epidermis
- Basal vacuolar change
- Lymphocytic exocytosis
- Satellite cell necrosis
- Marked upper dermal as well as superficial and deep perivascular lymphohistiocytic infiltrate