Linear IgA bullous dermatitis

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Clinical Features:

    • A group of IgA-mediated autoimmune blistering diseases with childhood or adult onset depending on the specific disease entity
    • Characteristic annular plaques with tense bullae around the edges
    • In some cases it is preceded by a viral infection or streptococcal throat infection.

    Histologic Features:

    • Subepidermal blisters containing neutrophils and smaller numbers of eosinophils and lymphocytes
    • Linear distribution of neutrophils along the dermal-epidermal junction
    • Papillary dermal edema
    • Immunofluorescence shows linear IgA and C3 along the dermal-epidermal junction.

    Cases associated with this book:

  • Linear IgA bullous dermatosis
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection