Microcystic adnexal carcinoma

    Clinical Features:

    • Indurated lesion, most common on the face
    • Most common in young women, but can be seen at any age
    • Frequently recur, but rarely if ever metastasize
    • Associated with prior radiation therapy

    Histologic Features:

    • Dermal islands and cords of epithelial cells with mild atypia, focally forming lumina and keratinous cysts
    • Mitotic figures are rare.
    • Fibrotic to sclerotic stroma
    • Invades deep into the dermis, and may infiltrate the subcutaneous fat, skeletal muscle and nerves
    External Links:

    Cases associated with this book:

  • Microcystic adnexal carcinoma
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection