Also known as: localized scleroderma, circumscribed scleroderma

Clinical Features:
Clinical Features:

• Represents a localized form of scleroderma
• Patients may rarely go on to develop systemic scleroderma.
• Most common in young to middle-aged women
• Controversial relationship with Borrelia burgdoferi
• Presents as indurated whitish plaques with a peripheral "lilac ring" rim.

Histologic Features:

• Early lesions:
  • Sclerosis of the reticular dermis
  • Superficial and deep perivascular lymphocytic infiltrate
• Later lesions:
  • Increasing sclerosis of the dermis with hyalinization and extension of the sclerosis into the subcutaneous fat
  • Atrophy and dropout of adnexal structures with "entrapment" of eccrine glands between sclerotic collagen bundles
  • Sometimes nodular collections of lymphocytes at the the dermal-subcutaneous junction
  • The epidermis is normal or atrophic.

Cases associated with this book:

Morphea
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection

Early deep dermal morphea
Author: Artur Zembowicz M.D. Ph.D.

Conference: Dr. Z's Consultations