Nephrogenic systemic fibrosis

    Clinical Features:

    • Disorder of unknown etiology affecting patients on renal dialysis
    • There is thickening and induration of the skin, most often on the trunk and limbs.

    Histologic Features:

    • Thickened dermis
    • The collagen bundles are arranged haphazardly throughout the dermis and subcutaneous septa.
    • Increased fibroblasts
    • Increased dermal mucin
    • Scattered multinucleated histiocytes spread throughout the dermis

    External Links:

    Cases associated with this book:

  • Nephrogenic dermopathy
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Teaching Collection