Also known as: cheilitis granulomatosa, Miescher-Melkersson-Rosenthal syndrome, granulomatous cheilitis

Clinical Features:

• Presents with lip swelling, sometimes with more extensive facial involvement, particularly affecting the eyelids
• The penis and vulva can be affected by similar lesions.
• Miescher-Melkersson-Rosenthal syndrome displays the triad of lep swelling, unilateral facial paralysis and a furrowed tongue.

Histologic Features:

• Non-necrotizing, poorly formed "naked" granulomas within the dermis
• Marked dermal edema
• Dilated dermal lymphatics
• Perivascular dermal lymphoplasmacytic infiltrate

Cases associated with this book:

Orofacial granulomatosis
Author: Stephen Lyle, M.D., Ph.D.

Conference: Dermpedia Teaching Collection