Clinical Features:

• Most common in young adults
• Present as multiple small, slow-growing, tender papules on the extremities or trunk
• Less commonly, may present as a larger solitary lesion, especially in males
• Some cases are falililal, with autosomal dominant inheritance.
• Associations include, HIV, CLL, erythrocytosis, uterine leiomyomas and papillary or collecting duct variants of renal cell carcinoma.

Histologic Features:

• Poorly defined dermal mass which merges imperceptibly with the surrounding dermal connective tissue
• Composed of interlacing fascicles of spindle cells with brightly eosinophilic cytoplasm and cigar-shaped nuclei
• Postitive for SMA, desmin, h-caldesmon and calponin

Cases associated with this book:

Pilar leiomyoma
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection