Pilar leiomyoma

    Article Contributors: 
    Sean Klepper M.D.
    Artur Zembowicz M.D....

    Clinical Features:

    • Most common in young adults
    • Present as multiple small, slow-growing, tender papules on the extremities or trunk
    • Less commonly, may present as a larger solitary lesion, especially in males
    • Some cases are falililal, with autosomal dominant inheritance.
    • Associations include, HIV, CLL, erythrocytosis, uterine leiomyomas and papillary or collecting duct variants of renal cell carcinoma.

    Histologic Features:

    • Poorly defined dermal mass which merges imperceptibly with the surrounding dermal connective tissue
    • Composed of interlacing fascicles of spindle cells with brightly eosinophilic cytoplasm and cigar-shaped nuclei
    • Postitive for SMA, desmin, h-caldesmon and calponin

    Cases associated with this book:

  • Pilar leiomyoma
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection