Clinical Features:

• Poikiloderma is a clinical term describing the features of mild scaling, atrophy, variations in pigmentation and telangiectasia.
• It is seen in a variety of diseases, including SLE, dermatomyositis, poikiloderma congenitale, congenital telangiectatic erythema, dyskeratosis congenita, poikiloderma of Civatte, Bloom's syndrome, Cockayne's syndrome, large plaque parapsoriasis and certain mitochondrial disorders.

Histologic Features:

• Hyperkeratosis
• Epidermal atrophy
• Basal vacuolar change
• Melanin incontinence
• Telangiectasia
• Upper dermal lymphohistiocytic infiltrate

Cases associated with this book:

Poikiloderma
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection