Clinical Features:

• Aggressive lymphoma seen on the lower legs of elderly patients, with a female predominance
• Presents as one or multiple red-brown or violaceous tumors
• Five-year survival of approximately 60%

Histologic Features:

• Diffuse dermal and subcuataneous infiltrate of atypical large lymphocytes with prominent nucleoli resembling immunoblasts or centroblasts
• Highly mitotically active
• A starry sky appearance may sometimes be seen.
• Positive for pan-B-cell markers, sometimes with loss of one or more markers
• bcl-2 is often positive, and CD10 and bcl-6 are variable
• Immunoglobulin light chain restriction can be demonstrated immunohistochemically in some cases.