Proliferating epidermal cyst

    Clinical Features:

    • Male predominance; most common in the anogenital region.  Also found on the scalp, upper extremities and trunk.
    • 20% incidence of carcinoma

    Histologic Features:

    • Multilocular epidermal inclusion cyst-type cystic spaces containing keratinous material within the dermis, sometimes connecting to the epidermis through a narrow opening
    • Epidermal-type keratinization must be present in order to make this diagnosis.
    • Suamous eddies may be seen.
    • The squamous epithelium may extend somewhat into the adjacent dermal stroma, but the lesion remains relatively circumscribed unless carcinomatous change has occurred.


    Cases associated with this book:

  • Proliferating epidermal cyst
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Dr. Z's Consultations