Clinical Features:

• Male predominance; most common in the anogenital region.  Also found on the scalp, upper extremities and trunk.
• 20% incidence of carcinoma

Histologic Features:

• Multilocular epidermal inclusion cyst-type cystic spaces containing keratinous material within the dermis, sometimes connecting to the epidermis through a narrow opening
• Epidermal-type keratinization must be present in order to make this diagnosis.
• Suamous eddies may be seen.
• The squamous epithelium may extend somewhat into the adjacent dermal stroma, but the lesion remains relatively circumscribed unless carcinomatous change has occurred.

Cases associated with this book:

Proliferating epidermal cyst
Author: Artur Zembowicz M.D. Ph.D.

Conference: Dr. Z's Consultations