Psoriasis

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Sharply demarcated, thick silvery plaques, most commonly on the scalp, trunk, buttocks, groin, elbows and knees
    • Familial in some cases, with linkage to certain HLA types
    • Patients may have nail dystrophy and/or psoriatic arthritis.

    Histologic Features:

    • Hyperparakeratosis
    • Regular acanthosis (rete ridges extend down to the approximately the same level)
    • Superpapillary thinning (epidermis is thin in areas overlying the dermal papillae)
    • Dilated capillaries within the dermal papillae
    • Perivascular lymphocytic infiltrate
    • Munro microabscesses (collections of neutrophils in the stratum corneum) and spongiform pustules of Kogoj (collections of neutrophils in the stratum spinosum)
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    Cases associated with this book:

  • Psoriasis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: Dr. Z's Consultations
  • Psoriasis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection
  • Psoriasis
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection