Clinical Features:

• Sharply demarcated, thick silvery plaques, most commonly on the scalp, trunk, buttocks, groin, elbows and knees
• Familial in some cases, with linkage to certain HLA types
• Patients may have nail dystrophy and/or psoriatic arthritis.

Histologic Features:

• Hyperparakeratosis
• Regular acanthosis (rete ridges extend down to the approximately the same level)
• Superpapillary thinning (epidermis is thin in areas overlying the dermal papillae)
• Dilated capillaries within the dermal papillae
• Perivascular lymphocytic infiltrate
• Munro microabscesses (collections of neutrophils in the stratum corneum) and spongiform pustules of Kogoj (collections of neutrophils in the stratum spinosum)

Cases associated with this book:

Psoriasis
Author: Stephen Lyle, M.D., Ph.D.

Conference: Dr. Z's Consultations

Psoriasis
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection

Psoriasis
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection