Sean Klepper M.D.
Stephen Lyle, M.D., ...
- Sharply demarcated, thick silvery plaques, most commonly on the scalp, trunk, buttocks, groin, elbows and knees
- Familial in some cases, with linkage to certain HLA types
- Patients may have nail dystrophy and/or psoriatic arthritis.
- Regular acanthosis (rete ridges extend down to the approximately the same level)
- Superpapillary thinning (epidermis is thin in areas overlying the dermal papillae)
- Dilated capillaries within the dermal papillae
- Perivascular lymphocytic infiltrate
- Munro microabscesses (collections of neutrophils in the stratum corneum) and spongiform pustules of Kogoj (collections of neutrophils in the stratum spinosum)