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Reactive perforating collagenosis

    Editor: unassigned

    Clinical features:

    • Rare genetic disorder. 
    • Characterized by hyperkeratotic papules following minor trauma, most commonly on the ams and hands.

    Histology:

    • Hyperkertotic plug "perforating" the epidermis
    • The plug and subjacent dermis contain collagen fibers and inflammatory cells: macrophages, giant cells, lymphocytes and especially neutrophils.
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    Differential Diagnosis (also link to): 

    Cases associated with this book:

  • Reactive perforating collagenosis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection