Clinical Features:

• Benign lesion, most commonly seen on the fingers and palms of young adults

Histologic Features:

• Well-circumscribed lesion in the dermis and/or subcutis
• Composed of hyalinized collagen with interspersed bland spindle cells, arranged in cords, bundles and whorls
• Immunohistochemically, the tumor cells are positive for EMA and negative for S-100.  Some cases are focally positive for CD34.

Cases associated with this book:

Sclerosing perineurioma
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection