Sclerosing perineurioma

    Clinical Features:

    • Benign lesion, most commonly seen on the fingers and palms of young adults

    Histologic Features:

    • Well-circumscribed lesion in the dermis and/or subcutis
    • Composed of hyalinized collagen with interspersed bland spindle cells, arranged in cords, bundles and whorls
    • Immunohistochemically, the tumor cells are positive for EMA and negative for S-100.  Some cases are focally positive for CD34.

    Cases associated with this book:

  • Sclerosing perineurioma
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: Teaching Collection