Clinical Features:

• Solitary skin-colored nodule
• Adults
• Cured by simple excision
• Multiple lesions may be seen in Cowden's disease, where they may occur in the oral cavity.

Histologic Features:

• Well-circumscribed dermal lesion
• Composed of bundles of hyalinized collagen bundles in a storiform pattern, separated by clefts
• Spindle cells are interspersed between the collagen bundles.
• Giant cell collagenoma is a variant that contains scattered multinucleated giant cells, which may have a bizarre appearance.

Cases associated with this book:

Sclerotic fibroma
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection