Clinical Features:

• Benign tumor most commonly presenting on the posterior aspect of the neck, shoulders or upper back
• Most common in older males
• Presents as a well-circumscribed, slowly growing subcutaneous, or rarely dermal, mass

Histologic Features:

• Admixture of mature adipose tissue and uniform spindle cells with pale eosinophilic cytoplasm
• Variable amounts of hyalinized collagen and occasional giant cells
• Lipoblasts are rarely present.
• Variable vascularity, sometimes with a focal hemangiopericytoma-like pattern
• Numerous mast cells are typically present.
• The spindle cells are positive for CD34 and negative for S-100.

External Links:

• Wikipedia

Cases associated with this book:

Spindle cell lipoma
Author: Artur Zembowicz M.D. Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection