Spindle cell lipoma

    Clinical Features:

    • Benign tumor most commonly presenting on the posterior aspect of the neck, shoulders or upper back
    • Most common in older males
    • Presents as a well-circumscribed, slowly growing subcutaneous, or rarely dermal, mass

    Histologic Features:

    • Admixture of mature adipose tissue and uniform spindle cells with pale eosinophilic cytoplasm
    • Variable amounts of hyalinized collagen and occasional giant cells
    • Lipoblasts are rarely present.
    • Variable vascularity, sometimes with a focal hemangiopericytoma-like pattern
    • Numerous mast cells are typically present.
    • The spindle cells are positive for CD34 and negative for S-100.

    External Links:

    Cases associated with this book:

  • Spindle cell lipoma
    Author: Artur Zembowicz M.D. Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection