Spongiotic erythema annulare centrifugum

    Article Contributors: 
    Sean Klepper M.D.
    Stephen Lyle, M.D., ...

    Clinical Features:

    • Large, annular scaly plaques, most commonly on the trunk of adults
    • May be idiopathic or secondary to a variety of conditions such as infections, autoimmune diseases, drugs or neoplasia.

    Histologic Features:

    • Superficial variant (more common):
      • Spongiosis with exocytosis and parakeratosis and papillary dermal edema 
      • Sharply demarcated superficial perivascular lymphocytic inflammation ("coat sleeve" or "cuffing")
    • Superficial and deep variant:
      • Normal epidermis
      • Lymphocytes "cuff" both superficial and deep blood vessels
    External Links:

    Cases associated with this book:

  • Erythema annulare centrifugum
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection