Clinical Features:

• Large, annular scaly plaques, most commonly on the trunk of adults
• May be idiopathic or secondary to a variety of conditions such as infections, autoimmune diseases, drugs or neoplasia.

Histologic Features:

• Superficial variant (more common):
  • Spongiosis with exocytosis and parakeratosis and papillary dermal edema 
  • Sharply demarcated superficial perivascular lymphocytic inflammation ("coat sleeve" or "cuffing")
• Superficial and deep variant:
  • Normal epidermis
  • Lymphocytes "cuff" both superficial and deep blood vessels

Cases associated with this book:

Erythema annulare centrifugum
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection