Sean Klepper M.D.
Artur Zembowicz M.D....
- Benign apocrine neoplasm which occurs on the head and neck in the vast majority of cases
- Plaque or nodule with a verrucous surface, often with oozing
- Sometimes associated with nevus sebaceus of Jadassohn
- Sometimes congenital
- Cured by simple excision
- Papillary projections into the lumen of a semicystic invagination in the epidermis
- The epithelial lining of the invagination is in continuity with the epidermis.
- The papillae are lined by a double layer of epithelium: an inner lining of cuboidal cells and an outer lining of apocrine-type cells with decapitation secretion.
- The cores of the papillae are densely packed with plasma cells.
- The base of the invagination displays tubular structures lined by tumor cells, which also grow superficially into the surrounding dermis.
- Mucinous metaplasia may sometimes occur.
- Mild cytologic atypia is sometimes present.