Thrombangiitis obliterans (Burger’s disease) is a vanishingly rare disease in USA, but is still a problem in some developing countries.
Clinical features of the disease include:

• Very strong association with smoking, especially unprocessed and unfiltered tobacco products.
• More common in males than females
• Painful violaceous lesions on distal extreminties, especially fingers and toes.
• Ulceration.
• Sensation of coldness.
• Resolution after cessation of smoking
• Visceral involvement exceptionally rare but can occur.
  

Histological features include:

• Involvement of small to medium sized arteries and (rarely) veins
• Intravascular thrombosis.
• Mixed inflammation infiltrate in vessel wall with numerous neutrophils
• Intravascular abscesses can be associated with intravascular thrombi or be present within a vessel wall
• Preserved internal elastic lamina
• Intravascular thrombi recanalize during resolution
  

External Links:

• Dermnet NZ
• Wikipedia