Tuberculoid granulomas

    Article Contributors: 
    Sean Klepper M.D.

    Tuberculoid granuloma is a term used for a granuloma composed of epithelioid histiocytes rimmed by lymphocytes, as opposed to sarcoidal ("naked") granulomas, which has few to no rimming lymphocytes.  There is some utility in making this distinction, as it can guide one's approach in forming a differential diagnosis, but it is important to not rely too heavily on the type of granulomas present in a lesion, since the distinction is not completely reliable: diseases which traditionally present with sarcoidal granulomas can sometimes show tuberculoid granulomas and vice versa.