Sean Klepper M.D.
Stephen Lyle, M.D., ...
- Form of generalized bullous pemphigoid that presents with large erythematous plaques, often with an annular appearance, usually without significant blistering
- Eosinophilic spongiosis
- Upper dermal inflammatory infiltrate composed primarily of eosinophils
- Usually no blister formation
- Immunofluorescence shows linear IgG and C3 at the dermal-epidermal junction, as in classic bullous pemphigoid.