Clinical Features:

• Form of generalized bullous pemphigoid that presents with large erythematous plaques, often with an annular appearance, usually without significant blistering

Histologic Features:

• Eosinophilic spongiosis
• Upper dermal inflammatory infiltrate composed primarily of eosinophils
• Usually no blister formation
• Immunofluorescence shows linear IgG and C3 at the dermal-epidermal junction, as in classic bullous pemphigoid.

Cases associated with this book:

Urticarial phase of bullous pemphigoid
Author: Stephen Lyle, M.D., Ph.D.

Conference: DermatopathologyConsultations.com Teaching Collection