Warfarin necrosis

Clinical Features:

 

  • Acute-onset purpura, sometimes with eschars or blistering, most commonly on the trunk and lower extremities
  • Associated with protein C deficiency
  • Ranges from mild and self-limted to fulminant and fatal

Histologic Features:

  • Epidermal necrosis with or without subepidermal blister formation
  • Dermal necrosis, thrombi and red blood cell extravasation

Cases associated with this book:

  • Warfarin necrosis
    Author: Stephen Lyle, M.D., Ph.D.

    Conference: DermatopathologyConsultations.com Teaching Collection