Sean Klepper M.D.
Stephen Lyle, M.D., ...
- Acute-onset purpura, sometimes with eschars or blistering, most commonly on the trunk and lower extremities
- Associated with protein C deficiency
- Ranges from mild and self-limted to fulminant and fatal
- Epidermal necrosis with or without subepidermal blister formation
- Dermal necrosis, thrombi and red blood cell extravasation