Dermpedia Courses are made available by Dermatopathology Consultations LLC (Boston, MA) www.dermatopathologyconsultations.com
|Opens:||02/29/2012 - 00:00|
|Closes:||12/30/2012 - 00:00|
|Pass rate:||75 %|
Dr. Samuel Moschella's Quiz: Ask, Show and Tell cases:
|Opens:||06/07/2011 - 00:00|
|Closes:||12/30/2013 - 00:00|
|Pass rate:||80 %|
This examination is intended for those participants of 2011 Comprehensive Course on Melanoma and Melanocytic Proliferations in Scottsdale, AZ who would like to claim American Board of Pathology Maintainance of Certification Self-Assessment Credits (SAMs). SAMs are provided by Community Medical Centers in Fresno, CA.
Community Medical Centers has been approved by the American Board of Pathology to provide Self-Assessment Modules (SAMs). SAMs are a specific form of Category 1 CME required by the ABP as part of its Maintenance of Certification Program.
Those who did not participate in the Course are welcome to take the test, but they are not eligible to claim CME and SAM Credits.
The test questions cover 10 hours of instruction at the Course, so successful participants can claim 10 SAM Credits.
All questions are based on the presentations delivered at the Course included in Course Materials. If you have not downloaded the Course Materials yet, the are available from www.dermatopathologyconsultations.com/education
80% of questions must be answered correctly in order to claim the credit.
Please review the questions carefully and review your notes and the Course Materials before answering each question as only 5 attempts will be allowed.
PhenoPath Laboratories is a physician-owned pathology reference laboratory providing diagnostic and contract research services to hospitals, physician offices, surgery centers, biopharmaceutical companies and research institutions nationwide.
PhenoPath Laboratories was founded by Dr. Allen M. Gown, one of the world's leading experts in the diagnostic and research applications of immunohistochemistry.
Cases from teaching files of Dr Artur Zembowicz, M.D., Ph.D., a principal consultant at:
Case collection featuring teaching and consultation cases of Dr. Artur Zembowicz, M.D., Ph.D., Professor of Pathology at Tufts Medical School,Founder of Dermpedia (bio) and a consultant in dermatopathology, ophthalmic pathology and head and neck pathology.
For more information about author and his consultation practice visit www.DermatopathologyConsultations.com
The main sourse of false-positive results in melanoma FISH is tetraploidy. In tetraploid cells increased number of intact chromosomes leads to increased signals with all FISH probes. In contrast, selective amplifications or deletions of genetic material is the most characteristic for melanoma. Importantly, not all the signals can be visible in a nucleus from a nevus cells as some FISH probe binding sites may not be in a place of section. Keeping this in mind answer the question which FISH result from the options bellow is most compatible with malignant melanoma?
Fluorescent in situ hybridization techniques have been used as an adjunct tool in the diagnosis of melanoma. It can be done either on formalin fixed, paraffin-embedded sections or on fresh-frozen tissue. A 4-probe multicolor melanoma FISH is the most commonly used and targets chromosomes 6 and 11. Each fluorescently labeled fragment of DNA that hybridizes to a tumor cell nucleus will appear as a distinct fluorescent dot. Each dot identifies a single copy of the chromosomal locus with a homologous DNA. Knowing that melanomas are characterized by chromosomal copy number aberrations, what is the best interpretation for the figure below?
Aqua: Cen 6
Acrodermatitis enteropathica can be an autosomal recessive inherited disorder or acquired, especially in patients with eating disorders or malabsorption conditions. The clinical syndrome is characterizd by a triad of acral dermatitis, alopecia, and diarrhea. What are the most common features found in the biopsy?
Macular arteritis is a recently described entity. It exhibits an indolent clinical course and is characterized clinically by asymptomatic erythematous and hyperpigmented macules and/or livido reticularis on the lower limbs. Which is true about macular arteritis?
Drug reactions can happen at any time after commencement of the treatment with a drug. Knowing the time-course of different drug eruptions can be helpful in identifying the offending drug. Which is not true about time-course of different types of drug eruptions?
Endocrine mucin producing carcinoma of the eyelid is a recently described lesion which is precursors to mucinous carcinoma of the eyelid. Which is not true about this tumor?
Sebaceous carcinomas of the eyelid is an aggressive tumor which is often misdiagnosed. Key histological features for the diagnosis includes: pagetoid spread, involvement of hair follicles, infiltrative growth, nests with comedo necrosis, and epithelioid cells with vesicular nuclei and bubbly vacuolated cytoplasm. In some cases it may extremely difficult to distinguish from basal cell carcinoma or squamous cell carcinoma.
Which is not true about ocular sebaceous carcinoma?
Pseudobowenoid changes of the vulva is an HPV-induced lesion described on the vulva which has similar histologic changes as seen in oral Heck’s disease (Focal epithelial hyperplasia). Both conditions are induced by rare HPV variants. Histological feature characteristic for these entities include epithelia hyperplasia with broad rete ridges, koilocytes, and presence of mitosoid bodies. Which types of HPV have been most associated with this disease?
Lyme disease is caused by a spiroquete Borrelia burgdorferi. It is transmitted by the Ixodes tick. Histologically, erythema chonicum migrans is characterized by a non-specific lymphocytic perivascular and perineural inflammatory infiltrate, usually associated with plasma cells. What other condition can be also associated with Lyme disease?
Which form of leprosy is characterized by well formed granulomas and scarce bacilli?