It has now been shown that this neoplasm can have which of the following features:
The following pigmented lesion shows wedge shape and symmetry, stromal fibroplasia, as well as dendritic cells and type A and B melanocytes. You confidently sign this case out as a “Blue nevus”. You realize that blue nevi :
This lesion was previously shaved, and carried a diagnosis of “Compound melanocytic nevus, extending to tissue edges”. The lesion repigmented 3 months later. You receive this biopsy from the scar and decide to:
The sections show a biopsy of a darkly pigmented well-circumscribed small (1 cm) pigmented lesion on a forearm of a 25 year old female.
The best diagnosis is?
This conjunctival entirely intraepithelial and clinically flat melanocytic proliferation from a 57 year old female according to WHO Classification of melanocytic proliferation is best reported as?
Myriad myPath Melanoma is a new diagnostic tool which uses a 23 gene expression signature for differentiating melanoma from nevi. It has been found that:
The image above indicates which of the following concerning this BAP 1 immunohistochemistry stain?
The lesion shown below is from the face of a 17 year old boy. It presented as a skin-colored papule. The clinical suspicion was Spitz nevus. The lesion was submitted for a second opinion as it did not express any of the melanocytic markers such as S100, MART1 or HMB45 even though the sections appear vaguely resembling Spitz nevus.
You are considering a diagnosis of cellular neurothecoma, a soft tissue tumor, which can be mistaken for a melanocytic neoplasm, especially Spitz nevus. The best way to confirm the diagnosis would be to perform which of the following immunohistochemical stains?
Which of the following features favor the diagnosis in the image?
The following neoplasm demonstrates the following immunohistochemistry profile: S100 (+), HMB45 (+), Melan A (+), MITF (+), c-KIT (-)
What feature(s) would direct you away from a diagnosis of melanoma:
Complete the following statement:
In general, patients whose tumors do not express PD-L1 on immunohistochemical studies, respond to anti PD-1/PD-L1 monotherapy ________________.
In nearly every state in the US, the statute of limitations (time during which litigation must be filed) begins to toll:
In order for a case of medical malpractice to foment, there must be:
Simple recurrent nevi often demonstrate: