2016 Yun Gene mutation and giant congenital nevus

    Multiple choice question

    Which gene mutation is mostly associated with giant congenital nevus?

    2016 Yun Subungual melanoma

    Multiple choice question

    Which of the following signs is clinical diagnostic clue for subungual melanoma

    2016 Yun Gene fusion and proper diagnosis

    Multiple choice question

    A 28 year-old male presented with bulky mass on his ankle.  The biopsy showed dermal tumor coposed of spindle and epithelioid cells with clear cytoplasm. Tumor cells were positive for S100 and HMB45.  Which gene fusion do you have to reveal for proper diagnosis?

    2016 Yun Gene fusion for proper diagnosis

    Multiple choice question

    A 28 year-old male presented with bulky mass on his ankle. The biopsy showed dermal tumor composed of spindle and epithelioid cells with clear cytoplasm. Tumor cells were positive for S100 and HMB45. Identification of which gene fusion would confirm the diagnosis?

    2016 Yun Vulva lesion diagnosis

    Multiple choice question

    A 45 year-old female presented with vulva lesion.  The biopsy showed junctional confluence of variable sized nests, and dermal nevoid cells. Nests were also spread along hair follicular epithelium. There was maturation with depth.  There were large cells with prominent nucleoli in upper dermal nests, but there were no mitoses. What is your best diagnosis?

    2016 Yun Diagnosis of acral melanoma

    Multiple choice question

    Which feature is most important for the diagnosis of acral melanoma rather than acral nevus?

    2016 Yun Features of Acral melanoma

    Multiple choice question

    Which dermoscopic feature is mostly suggestive of acral melanoma?

    2016 Yun mutation subtype and UV

    Multiple choice question

    Which mutation subtype is mostly associated with lack of UV signature?

    2016 Yun GNAQ and GNA11

    Multiple choice question

    Which melanoma is mostly associated with GNAQ and GNA11 mutations?

    2016 Dadras microRNA

    Multiple choice question

    Which microRNA has been proven to distinguish nevus from melanoma cells by in situ hybridization?

    2016 Rabkin Characteristics linked to melanoma status

    Multiple choice question

    Which of the following characteristics of nevi in case-control studies comparing nevi removed from melanoma patients and spouse controls was linked to melanoma?

    2016 Chan Melanocytic nevi in pregnancy

    Multiple choice question

    All of the following may be seen in melanocytic nevi (example shown below) excised during pregnancy EXCEPT:

    2016 Mihm Tumor Infiltrating Lymphocytes

    Multiple choice question

    Tumor Inflitrating Lymphocytes:

    2016 Mihm Ulceration

    Multiple choice question

    Ulceration

    2016 Mihm AJCC

    Multiple choice question

    The most important prognostic factors recognized by the AJCC 7th edition are:

    2016 Mihm Childhood tumor

    Multiple choice question

    Malignant melanoma in childhood:

    2016 Mihm Atypical Spitz tumors

    Multiple choice question

    Atypical Spitz's tumors:

    2016 Lowe nodal nevi

    Multiple choice question

    All of the following are correct regarding nodal nevi except:

    2016 Lowe metastatic tumor deposits

    Multiple choice question

    Which of the following is the most common location for metastatic tumor deposits in a sentinel lymph node?

    2016 Clarke myPath Melanoma test

    Multiple choice question

    Which of the following are potential sources of apparent false positives with Myriad's myPath Melanoma test?

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