Case for 2014 Dermpedia Hematopathology Conference. Xanthogranuloma?

    A 41-year-old woman had CD30(+) nodal anaplastic large T-cell lymphoma of the neck diagnosed. Six courses of chemotherapy (CEOP, cyclophosphamide, epirubicin, vincristine, and prednisone) were given and the patient recovered well.

    Unfortunately, acute myeloid leukemia was found in 2 years later and high dose Ara-C chemotherapy was arranged.  Multiple rash occurred on her face during the 2nd chemotherapy.

    Case for 2014 Dermpedia Hematopathology Conference. Leukemia cutis?

    A 9-month-old full-term boy was admitted due to fever, abdominal distension and diarrhea for 2 weeks. Hepatosplenomegaly was noted and the blood test and bone marrow examination showed acute myeloid leukemia. 

    Several brownish to erythematous nodules and plaques were noted on his scalp. A skin biopsy was taken under the impression of leukemia cutis.

    Case for 2014 Dermpedia Hematopathology Conference. T or B cell Lymphoma?

    A 32 year-old man had fever and night sweating for 2 weeks. He had multiple indurated dusky red plaques with mild local tenderness appeared rapidly on his limbs and back.

    Case for 2014 Dermpedia Hematopathology Conference. Papular granuloma annulare?

    A 41-year-old man has many skin-colored papules on his elbow, neck and abdomen. Some of them are present on annular erythematous patches which KOH exam was positive for fungus.

    Case for 2014 Dermpedia Hematopathology Conference. Mycosis fungoides?

    A 71-year-old woman has many reddish or brown morbiliform macules, papules, patches on her trunk and 4 limbs for several months. 

    Case for 2014 Dermpedia Hematopathology Conference. What kind of papulonecrotic disease is it?

    A 8-year-old boy has recurrent skin lesions with crusted ulceration on his face and limbs. He has similar rash happened intermittently since one year old. Blood tests including CBC, CRP, ANA, RF, C3, C4, HIV, phogocyte functions have been done but all showed normal findings. 

    Case for 2014 Dermpedia Hematopathology Conference: Large B Cell Lymphoma: Are you sure?

    A 54 year old male presented with 3-4 cm irregular erythematous nodule on the forehead. A biopsy was performed.

    The case was initially interpreted as possible diffuse large  B cell lymphoma. However, the clinician was skeptical of the diagnosis and the staging was negative.

    What isthe  correct diagnosis?

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    Case for 2014 Dermpedia Hematopathology Conference: Large Lymphoma: What type?

    79 yo male referred for evaluation of recently appearing rash involving legs and torso. The patient was well-appearsing and asymptomatic. Dermatologist biopsied the largest 2.5 cm red erythematous plaque. Clinical ddx included vasculitis, Sweets, hypersensitivity reaction, disseminated herpes zoster, metastasis, leukemia cutis vs atypical infectous process

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    Case for 2014 Dermpedia Hematopathology Conference: Large Lymphoma: What type?

    66 year old Caucasian woman presented with 2 cm erythematous nodule on the right leg.
    Staging work  up was negative.

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    Case 3 for 2014 Dermpedia Hematopathology Conference.

    The patient was a 65 year old female with diffuse erythematous rash which was unuccessfully treated as eczema. The biopsy was performed with clinical information: “?eczema, r/o CTCL” . 

     

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