2016 Tse GNAQ-mutant MMN

    Multiple choice question

    Which of the following secondary genomic alterations drives the metastatic potential of GNAQ-mutant malignant melanocytic neoplasms?

    2016 Elvin High tumor mutation

    Multiple choice question

    High tumor mutation burden may differentiate patients most likely to respond to which of the following melanoma therapies (pick all that apply)

    2016 Elvin Testing for BRAF

    Multiple choice question

    Testing only for BRAF base substitutions is adequate for identifying patients who may respond to targeted therapy in which of the following:

    2016 Elder Key role of pathologist

    Multiple choice question

    The key role of the pathologist in the diagnosis of atypical (intermediate) melanocytic lesions is to:

    2016 Elder Characteristics of melanomas in high CSD

    Multiple choice question

    Characteristics of melanomas in high CSD (chronic solar damage) skin include:

    2016 Elder Staining for p16

    Multiple choice question

    Staining for p16 in a Spitz nevus/tumor is appropriately used to:

    2016 Elder CSD Skin Spitz/PSCN

    Multiple choice question

    A succinct histologic definition of a Spitz nevus/tumor is:

    2016 Elder sclerosing atypical nevi

    Multiple choice question

    Which statement regarding so-called sclerosing atypical nevi (fibrosing dysplastic nevi) is correct?

    2016 Elder Superficial MN

    Multiple choice question

    Nevi are important mainly in relation to melanoma

    2016 Elder Recurrent MN

    Multiple choice question

    In a recurrent melanocytic nevus

    2016 Elder Superficial Melanomas

    Multiple choice question

    Criteria for diagnosis of melanoma are:

    2016 Zembowicz Syringotropic melanoma

    Multiple choice question

    Syringotropic melanoma is defined as melanoma in situ spreading along eccrine ducts at depth greater than melanoma invading from the epidermis. Syringotropic melanoma can invade deep in the reticular dermis and subcutaneous tissue from within eccrine apparatus. Such syringocentric foci of invasion can be occult clinically.  

     

    Which statement regarding involving of eccrine ducts by melanocytic proliferations is not correct?

    2016 Zembowicz Conjunctival Nevi

    Multiple choice question

    The sections show a biopsy of a conjunctival pigmented lesion. The lesion is associated with prominent conjunctival cysts.

     

     

     

    Which statement regarding conjunctival cysts in melanocytic proliferations of the conjunctiva is correct?

    2016 Zembowicz PEM

    Multiple choice question

    Images below are from a biopsy of a slowly-growing (years) pigmented lesion in a young patient from a family with Carney complex. The best diagnosis in this case is?

     

     

     

     

    2016 Zembowicz Melanoma FISH

    Multiple choice question

    Which statement about flourescence in situ hybridization in melanoma is not correct?

    2016 Zembowicz Malignant blue nevus

    Multiple choice question

    Which statement about malignant blue nevus/melanoma arising in blue nevus is not correct?

    2016 Elder Intermediate ML

    Multiple choice question

    Intermediate melanocytic lesions are characterized by:

    2016 Elder Epidemiology

    Multiple choice question

    Evidence for the solar hypothesis of melanoma etiology includes:

    2016 de la Fouchardiere NvM

    Multiple choice question

    Variants Nevoid melanoma (NvM), which is true?

    2016 de la Fouchardiere DM

    Multiple choice question

    Which statement about desmoplastic melanoma (DM) is true?

     

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