A 78-year-old female presented with an erythematous crusted palque-like lesion on the right dorsal foot.
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Histrogical findings : Hyperkeratosis with parakeratosis is overlying the full-thickness dysplastic epidermis with loss of maturation and lack of polarity of cells. The tumor cells contain marked irregular hyperchromatic nuclei with conspicuous nucleoli and abundant cytoplasm. Individually keratinized cells are also seen.
This 44-year-old male presented with hyperkeratotic papules on the forehead, neck, behind the ear and in the groin area. Small depigmented macules on the trunk and upper limbs were also noted as well as skin colored flat surfaced papules on the dorsa of the hands and feet. Palmoplantar pitting and nail changes were also present.
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Histological examination shows a cystically dilated follicle communicating with the epidermis. Numerous secondary follicles are present.